light-chain isotype

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• Immunoglobulin light chain — Schematic diagram of an typical antibody showing two Ig heavy chains (blue) linked by disulfide bonds to two Ig light chains (green). The constant (C) and variable (V) domains are shown …   Wikipedia

• Isotype (immunology) — In immunology, the immunoglobulin isotype refers to the genetic variations or differences in the constant regions of the heavy and light chains of the Ig (immunoglobulins)classes and sub classes. In humans, there are nine isotypes:* heavy chain… …   Wikipedia

• isotype switching — The switch of immunoglobulin isotype that occurs, for example, when the immune response progresses (IgM to IgG). The switch from IgM to IgG involves only the constant region of the heavy chains (from m to g ), the light chain and variable regions …   Dictionary of molecular biology

• isotype — (1) Applied to a set of macromolecules sharing some features in common. In immunology isotype describes the class, subclass, light chain type and subtype of an immunoglobulin. (2) Antigenic determinant that is uniquely present in individuals of a …   Dictionary of molecular biology

• isotype — An antigenic determinant (marker) that occurs in all members of a class or subclass in the heavy chains of an immunoglobulin or in the type and subtype of light chains of an immunoglobulin molecule. Whereas a given allotypic …   Medical dictionary

• L-chain — (= light chain) Although light chains are found in many multimeric proteins, L chain usually refers to the light chains of immunoglobulins. These are of 22 kD and of one of two types, kappa ( k ) or lambda ( l). A single immunoglobulin has… …   Dictionary of molecular biology

• Heavy chain — A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig… …   Wikipedia

• Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

• Immunoglobulin — A protein produced by plasma cells and lymphocytes. Immunoglobulins are an essential part of the body s immune system which attach to foreign substances, such as bacteria, and assist in destroying them. Abbreviated Ig. The classes of… …   Medical dictionary

• V(D)J recombination — V(D)J recombination, also known as somatic recombination, is a mechanism of genetic recombination in the early stages of immunoglobulin (Ig) and T cell receptors (TCR) production of the immune system. V(D)J recombination nearly randomly combines… …   Wikipedia

• Anticuerpo — Molécula de inmunoglobulina con su típica forma de Y. En azul se observan las cadenas pesadas con cuatro dominios Ig, mientras que en verde se muestran las …   Wikipedia Español